The sudden surge of high current in a short circuit makes the fuse wire melt, or blow, breaking the circuit. When this happens, see if there is a short circuit or a disconnection, then install a new fuse of the correct amperage rating (See Checking and replacing fuses).
All the electrical units of measurement are interrelated: a pressure of 1 volt causes a current of 1 amp to flow through a resistance of 1 ohm. Volts divided by ohms equal amps. For example, a light bulb with a resistance of 3 ohms, in a 12 volt system, consumes 4 amps.
Some components must be connected in series. For example, the sender in the fuel tank varies its resistance according to the amount of fuel in the tank, and sends a small electrical current to the fuel gauge.
There are many fuses, each protecting a small group of components, so that one blown fuse does not shut down the whole system. Many of the fuses are grouped together in a fuse box, but there may also be line fuses in the wiring.